Cunliffe-awards.de



CURRICULUM
William James CUNLIFFE,
F.R.C.P.
CONTENTS
PERSONAL DETAILS, DEGREES, DISTINCTIONS, PRIZES PREVIOUS AND PRESENT APPOINTMENTS PRESENTATIONS National and International GUEST LECTURES National and International CHAIRMAN - International Symposia and Poster Awards LEARNED JOURNAL COMMITMENTS COMMITTEE ACTIVITIES - National and International HONORARY MEMBERSHIP OF OVERSEAS SOCIETIES SUPERVISION OF HIGHER DEGREES 1. NAME William James CUNLIFFE Date of birth 28.12.1939 DEPARTMENTAL ADDRESS 47, Tredgold Avenue, Department of Dermatology, The General Infirmary at Leeds, Great George Street, Tel. 0044-(0)113-292-3605 FAX 0044-(0)113-234-1154 B.Sc. (Anatomy - 1st Class Honours) M.B., Ch.B. (Manc.) (Honours) 4. DISTINCTIONS Anatomy Pharmacology Medicine 5. PRIZES Undergraduate State Daniel Thwaites Scholarship Prosector in Anatomy Theodore Gregory Prize Dauntsey Senior Medical Scholarship Scholarship in Anatomy, Physiology & General Science Honorary Scholarship in Medicine Turner Medical Prize Dumville Surgical Prize Raper Prize in Physiology and Medicine Ernest Hart and Walter Dixon (B.M.A. Scholarship) European Society for Dermatological Research, F. Serri Poster award P. Bowden, P. Bladon, E. Wood, W.J. Cunliffe "Biosynthesis of Human Scalp Skin Proteins by in vitro Translation of Isolated Messenger RNA" European Society for Dermatological Research, F. Serri Poster award P. Bladon, P. Bowden, E. Wood, W.J. Cunliffe "mRNA Levels in Psoriatic Epidermis" XVII World Congress of Dermatology, Berlin, The Honorary Medal European Society for Dermatological Research, F. Serri Poster award J.H. Cove, E.A. Eady, C. Goodwin, E. Ingham, W.J. Cunliffe "Modulation of Comedonal IL-1 Levels in Acne Patients Treated with Tetracyclines" European Hair Research Society, Best Clinical Poster Prize M. Nutbrown, S. Macdonald Hull, V. Randall, W.J. Cunliffe "The role of melanocytes in sub-clinical alopecia areata" PREVIOUS APPOINTMENTS House Physician to Professor Black and Professor Stanbury, Manchester Royal Infirmary House Surgeon to Professor Boyd, Manchester Royal Infirmary Demonstrator and Assistant Lecturer to Professor Campbell, Department of Pathology, Manchester University Senior House Officer to Dr. Howat, Consultant Physician, Manchester Royal Infirmary Temporary Lecturer in University December 1965 - September 1966 Department of Dermatology, Royal Victoria Infirmary, Newcastle-upon-Tyne Royal Victoria Infirmary, Newcastle-upon-Tyne Senior Registrar, Royal Victoria Infirmary, Newcastle-upon-Tyne PRESENT APPOINTMENT Consultant Dermatologist, United Leeds Teaching Hospitals NHS Trust, The General Infirmary at Leeds Honorary Senior Lecturer University of Leeds Honorary Professor of Dermatology SUMMARY
I have been on the senior staff at The General Infirmary at Leeds and the University of Leeds, Leeds since 1969 and have
four major roles - clinical, teaching, research and administration.
CLINICAL
Each week I see about 40 new patients and 100 old patients in clinics at The General Infirmary. There are 16 dermatology
beds, which are shared by 4 consultants.
My main interests are - acne vulgaris, acne scarring and clinical trials on acne and psoriasis. Fifteen percent of the acne
referrals are from other Yorkshire hospitals and a further 5% are from outside Yorkshire.
I have published, or been co-author of, 439 papers.
ADMINISTRATION
1. Hospital - My administrative role has been within the department, along with Dr. M.J. Goodfield and Dr. R. Sheehan-
Dare. I play no major role in the general hospital politics.
2. National - I have been active at a national level, having been Chairman of the British Association of Dermatologists
(Investigative Group), executive member of the British Association of Dermatologists and Chairman of The Skin Club
research group. I was also Chairman of the British Association of Dermatologists Therapy Sub-Group.
3. International - I have been the English representative of the European Society for Dermatological Research for 6 years.
During this time I was Secretary for 3 years and President for 1 year. Currently, I am on the Scientific Committee of the
European Academy of Dermatology and Venereology.
GUEST LECTURES
I have given 2 named Orations in the U.K. and made 196 national and 211 international presentations to learned societies.
UNDERGRADUATE TEACHING
All 200 students have a 5 week session in dermatology. I have a teaching clinic most weeks and have overall responsibility
for each group of students and, should they fail their dermatology MCQ and pictorial quiz, I viva them in a pass/fail
situation. I also give 6-8 lectures annually to students from other University disciplines on skin and its function in health
and disease.
POSTGRADUATE TEACHING
(a) Departmental Medical Staff
(i) I teach the Specialist Registrars in the department on an apprentice basis in the clinic and on the wards.
(ii) Every 4 weeks I meet all Specialist Registrars in order to discuss clinical problems, their career and research.
(iii) In conjunction with our senior resident, I organise our weekly grand round, this consists of a ward round, discussion of
problematic ward cases, presentation of difficult out-patient cases, a seminar and journal club.
(iv) I organise our monthly academic session (clinical cases and invited lecturers).
(b) General Practitioners
I regularly have 2 trainee GPs sitting in one clinic a week.
(c) Departmental Scientific Staff
The number of scientific staff varies according to available funds. In 1997 I support (through the Leeds Foundation for
Dermatological Research - A Registered Charity) 5 post doctoral fellows, 6 science graduates - of whom 3 are currently
doing a Ph.D. - and 3 technicians.
HIGHER DEGREES The Department of Dermatology is an integral part of the University of Leeds Skin Research Centre and I am on the managerial committee. I supervise, either alone or jointly, the higher degrees of the medical and scientific staff attached to the department. To date 7 colleagues have obtained an M.D. and 16 a Ph.D. RESEARCH My main research interests relate to acne and scars, alopecia areata and cutaneous microbiology and I am Chairman and Director of the Leeds Foundation for Dermatological Research. I am also Clinical Director of the University of Leeds Skin Research Centre. We are a multi-disciplinary group financing its research from the MRC, Wellcome, other charities, industry and patient donations so that in one year (such as 1997) 28 people are actively undertaking human skin research in a co-ordinated manner. The advantage of the Skin Research Centre is the presence of a core of colleagues who have permanent contracts with the University or NHS - Dr. E.J. Wood (Reader in Biochemistry); Professor K.T. Holland (Department of Microbiology); Dr. E. Ingham (Senior Lecturer in Immunology) and myself. The group has published over 450 scientific papers, of which I am a co-author of 391. PUBLICATIONS
1961-1997
1-411
Comparison of the yeast Saadatzadeh M.R. mycelial antigens of Malassezia 138, 742 Cunliffe
The Sebaceous Gland and Acne - Dermatology Cunliffe
414. Propionibacterium acnes Dermatology Cunliffe
Resistance to erythromycin and Clindamycin in cutaneous propionibacteria is associated with mutations in Cunliffe
Inflammation in acne vulgaris: failure of skin micro-organisms to modulate keratinocyte Cunliffe
Variation in pilosebaceous Dermatology Aldana proliferation in acne Cunliffe
The compliance of renal transplant recipients with advice about sun measures Cunliffe
Adapalene: a new topical treatment Prescriber Cunliffe
A comparison of the efficacy and Eur J Dermatol Cunliffe
safety of lymecycline and minocycline in patients with moderately severe acne vulgaris Acne vulgaris in the elderly: the response to low-dose 139, 99-101 Cunliffe
Differential response of sebaceous glands to exogenous 139, 102-103 Cunliffe
A new topical retinoid - why a Br J Dermatol Cunliffe
new topical acne therapy? 139, Suppl. 52, 1-2 A comparison of the efficacy and Br J Dermatol Cunliffe
tolerability of adapalene 0.1% 139, Suppl. 52, 48- gel versus tretinoin 0.025% gel in patients with acne vulgaris: a meta-analysis of five randomised trials 417. Immunohistochemical investigation of evolving inflammation in lesions of Cunliffe
Oral isotretinoin is not J Dermatol Treatment associated with increased 9, 211-213 Cunliffe
side-effects when prescribed The Leeds revised acne J Dermatol Treatment Cunliffe
16S rRNA mutation associated with tetracycline resistance Agents & Chemotherapy in a Gram-positive bacterium Cunliffe
The clinical significance of Propionibacterium acnes Literature - Cunliffe
resistance in acne management Dermatology Cost-Effectiveness of Oral Dermatology Cunliffe
van deKerkhof PCM Practitioner Cunliffe
Childhood/adolescent acne: a Current Paediatrics review of aetiology and 9, 1-6 Cunliffe
The familial risk of adult acne: a comparison between first-degree relatives of Cunliffe
affected and unaffected individuals 434. The treatment of acne fulminans: a review of 25 141, 307-309 Cunliffe
Acne fulminans sine fulminans Dermo focus Cunliffe
Light cautery of macrocomedones under general (Letter) Cunliffe
The treatment of acne agminata 141, 596-597 Cunliffe
A Placebo-Controlled Clinical Dermatology Glass Trial to Compare a Gel Containing a Combination of Isotretinoin (0.05%) and Erythromycin (2%) Cunliffe
with Gels Containing Isotretinoin (0.05%) or Erythromycin (2%) alone in the Topical Treatment of Prevalence of facial acne in J Am Acad Dermatol Cunliffe
Oral trimethoprim: a relatively Br J Dermatol Cunliffe
safe and successful third-line treatment for acne vulgaris The inter-relationship between J Euro Acad Dermatol isotretinoin/acne and & Venereol Cunliffe
Phototherapy and acne vulgaris Br J Dermatol Cunliffe
The cutaneous microflora of adolescent, persistent and late- onset acne patients does not Cunliffe
Comedogenesis: some new Br J Dermatol Cunliffe
aetiological, clinical and 142:1084-1091 Holland therapeutic strategies Management of adult acne and J Cut Med & Surg Cunliffe
2 (Suppl. 3), (In Press) The following were written or edited with single or dual authorship:- "The Acnes. Clinical Features, Pathogenesis and Treatment" Vol. 6 - Major Problems of Dermatology. (1975) W.J. Cunliffe and J.A. Cotterill
Published by W.B. Saunders & Co., London. 1989 "Acnes W.J. Cunliffe
Published by Martin Dunitz Ltd., London. Co-editor of Symposium Proceedings:- "Retinoid Therapy" (1984) W.J. Cunliffe and A.J. Miller
Published by MTP Press, Lancaster. The following Chapters were written with single or multiple authorship:- "A method of Measuring Well-Defined Areas Within Sections Applied to the Assessment of Tissue Fibrinolysis" W.J. Cunliffe, E.A. Dodman and J.A. Webster (1972) p.104-110
IN: Handbook of the Microcirculation Society "Fibrinolytic Therapy of Vasculitis" Cunliffe, B. Dodman, B.E. Roberts, R. Sibbald (1972)
IN: 8th Symposium on Advance Medicine "Methods for Microbiological Investigation of Acne" K.T. Holland and W.J. Cunliffe (1979) p.21-35
"Investigation of Fibrinolytic Activity" Cunliffe (1979) p.144-150
IN: Investigative Techniques in Dermatology Published by Blackwell Scientific Publications, Oxford, London. 1979 "Necrobiotic Cunliffe and J.M. Beare (1980)
"Histiocytic Proliferative Disorders" Cunliffe and J.M. Beare (1980)
"Benign Lymphplasis of the Skin" Cunliffe and J.M. Beare (1980)

"Mastocytosis"
W.J.
Cunliffe and J.M. Beare (1980)
"Disorders of the Connective Tissues" Cunliffe (1980)
"The Subcutaneous Fat" Cunliffe and S.S. Bleehen (1980)
"The Skin and the Nervous System" Cunliffe (1980)
IN: Textbook of Dermatology (3rd edition) Eds. A. Rook, D.S. Wilkinson and F.J.G. Ebling Published by Blackwell Scientific Publications, Oxford, London, Edinburgh, "Hormonal Control of Sebaceous Glands with Special Reference to Anti- Androgens Applied Topically" Cunliffe and N.B. Simpson (1980) p.149-154
IN: Percutaneous Absorption of Steroids" Eds. P. Mauvais-Jarvis, C.F.H. Vickers and J. Wepierre Published by Academic Press Inc. (London) Ltd. "Techniques in the Investigation of Acne" Cunliffe (1980) p.75-94
IN: Dermatology Symposia in Lund - Acne Eds. L. Juhlin, H. Rorsman, J.S. Strauss Published by Draco - Tika. "Retinoic Acid in Dermatology" Cunliffe (1981) p.157-185
IN: Vitamins in Human Biology & Medicine Published by CRC Press, Florida. "13-cis-Retinoic Acid in Acne. (A Double-Blind Study of Dose Response)" D.H. Jones, W.J. Cunliffe and J. Cove (1981) p.255-258
IN: Retinoids: Advances in Basic Research and Therapy Ed. C.E. Orfanos et al. Published by Springer-Verlag, Berlin, Heidelberg, New York. "A Modified Photometric Technique for Measuring Sebum Excretion Rate" Cunliffe, J.N. Kearney and N.B. Simpson (1981) p.183-185
IN: Bioengineering and the Skin Eds. R. Marks and P.A. Payne Published by M.T.P. Press Ltd., Lancaster. "Isolation and Charterization of Different Keratin Types from Human P.E. Bowden and W.J. Cunliffe (1983) p.9-18
IN: Stratum Corneum Eds. R. Marks and G. Plewig Published by Springer-Verlag, Berlin, Heidelberg, New York. "A Dose Response Study of 13-cis-Retinoic Acid Therapy in Cystic Acne" D.H. Jones, W.J. Cunliffe, K. King and A.J. Miller (1983) p.203-213
"A Follow-up Study of 13-cis-Retinoic Acid Therapy in Cystic Acne" D.H. Jones and W.J. Cunliffe (1983) p.241-251
"13-cis-Retinoic Acid in Acne - Mechanism of Action" Cunliffe, D.H. Jones, K.T. Holland, S. Millard and H. Al-Baghdadi
(1983) p.255-266 "Isotretinoin and Oral Contraceptive Steroids" M. Orme, D.J. Back, W.J. Cunliffe, D.H. Jones, W.L. Allen and J. Tjia
(1983) p.277-283 "A Comparative Study of 13-cis-Retinoic Acid and Erythromycin Therapy in Severe Acne" W.J. Cunliffe and A. Loffler (1983) p.293-301
"The Management of Cystic, Conglobate and Severe Acne Irresponsive to Systemic Antibiotics with Roaccutane" A.J. Miller and W.J. Cunliffe (1983) p.349-364
IN: Retinoid Therapy. A Review of Clinical and Laboratory Research Eds. W.J. Cunliffe and A.J. Miller
Published by MTP Press Ltd., Lancaster, Boston, The Hague, Dordrecht. "Acne Caused and Treated by Topical Agents" Cunliffe (1985) p.11-22
IN: Topics in Topicals Published by MTP Press, Lancaster. "Long-Term Benefit of Isotretinoin in Acne" Cunliffe, D.H. Jones, J. Pritlove, D. Parkin (1985) p.242-251
IN: Retinoids: New Trends in Research and Therapy Published by S. Karger AG, Basel. 1986 "Necrobiotic Cunliffe (1986) p.1687-1697
"The Subcutaneous Fat" J.L. Burton and W.J. Cunliffe (1986) p.1859-1879
"The Sebaceous Glands" F.J.G. Ebling and W.J. Cunliffe (1986) p.1897-1936
"The Skin and the Nervous System" Cunliffe and J.A. Savin (1986) p.2229-2255
IN: Textbook of Dermatology (4th edition) Eds. A.J. Rook, D.S. Wilkinson, F.J. Ebling, R.H. Champion, J.L. Burton Published by Blackwell Scientific Publications, Oxford, London, Edinburgh, "Human Model for Acne" Cunliffe (1986) p.2-12
IN: Skin Models - Models to Study Function and Disease of Skin" Eds. R. Marks and G. Plewig Published by Springer-Verlag, Heidelberg. "Management of Acne" Cunliffe (1986) p.313-320
IN: The Royal College of General Practitioners Members' Reference Book
1987 "Acne"
W.J.
Cunliffe (1987) p.1-27
IN: Treatment in Dermatology (New Clinical Applications. Dermatology) Published by MTP Press Ltd., Lancaster, Boston, The Hague. "The Sebaceous Gland as a Source of Androgen - an Hypothesis" N.B. Simpson, W.J. Cunliffe, M. Rademaker, C. Stewart and A.M. Wallace
"Measurement of the Follicular Reservoir Using Sebum Absorption into Bentonite Clay" B.R. Hughes and W.J. Cunliffe (1989) p.43-44
"Cell Envelope Production in Acne" H.T. Rupniak, D.M. Turner, W.J. Cunliffe, R. Dhuna, M.R. West (1989) p.87-91
and "Keratin Characterization in the Pilosebaceous Ducts of Acne Patients" A.R. Kluznik, E.J. Wood and W.J. Cunliffe (1989) p.113-114
"The Therapeutically Difficult Patient" Cunliffe and B. Hughes (1989) p.147-158
"The Effect of Isotretinoin on the Pilosebaceous Duct in Patients with Acne" B.R. Hughes and W.J. Cunliffe (1989) p.223-226
"A Comparison of Topical Azelaic Acid and its Base in the Treatment of Acne" J.F.B. Norris, B.M. Burke and W.J. Cunliffe (1989) p.237-240
"A comparison of the Effectiveness of Oral Oxytetracycline, Benzoyl Peroxide Gel and Topical Tetracycline in the Treatment of Acne" J.F.B. Norris, B.R. Hughes, A.J. Basey and W.J. Cunliffe (1989) p.261-265
"The Effects of Oral Erythromycin Therapy for Acne on the Development of Resistance in Cutaneous Staphylococci and Propionibacteria" E.A. Eady, J.I. Ross, J.H. Cove, K.T. Holland and W.J. Cunliffe (1989)
IN: Acne and Related Disorders Eds. R. Marks and G. Plewig Published by Martin Dunitz Ltd., London. Cunliffe (1989) p.473-483
IN: Accident and Emergency Medicine Eds. WH Rutherford, RN Illingworth, AK Marsden, PG Nelson, AD Redmond and Published by Churchill Livingstone, Edinburgh. "Measurement of Human Sebaceous Gland Function" Cunliffe (1989) p.22-26
IN: Handbook of Experimental Pharmacology, Vol. 87/II. Pharmacology of the Eds. M.W. Greaves and S. Shuster Published by Springer-Verlag, Berlin Heidelberg. "Isotretinoin and Acne: A Long-Term Study" Cunliffe, A. Layton, H.E. Knaggs, J. Stubbings and J.P. Taylor (1991)
IN: Retinoids:10 Years On Ed. J.-H. Saurat Published by S. Karger AG, Basel. Cunliffe (1991)
IN: Therapeutic Drugs Ed. Sir Colin Dollery Published by Churchill Livingstone, Edinburgh. "Disorders of the Sebaceous Glands" F.J. Ebling and W.J. Cunliffe (1992) p.1699-1744
and "Necrobiotic Cunliffe (1992) p.2027-2039
and "Subcutaneous J.L. Burton and W.J. Cunliffe (1992) p.2135-2162
IN: Textbook of Dermatology (5th edition) Eds. R.H. Champion, J.L. Burton and F.J.G. Ebling Published by Blackwell Scientific Publications, Oxford. "The Role of the Cutaneous Microflora in Host Defence and its Response to the Environment" J.H. Cove, E.A. Eady, J.L. Tipper and W.J. Cunliffe (1992) p.385-389
IN: The Environmental Threat to the Skin Eds. R. Marks and G. Plewig Published by Martin Dunitz Ltd., London. 1993 "Akne" W.J. Cunliffe and H. Gollnick
Published by Martin Dunitz Ltd., London. "New Approaches to Acne Treatment" (1994) W.J. Cunliffe
Published by Martin Dunitz Ltd., London. "Skin Therapy" (1994) Eds. R. Marks and W.J. Cunliffe
Published by Martin Dunitz Ltd., London. "El Paciente Terapéuticamente Difícil IN: Acne-Manejo Racional 2da edición Ed. J. Piquero Martín Published by Panamericana Formas e Impresos S.A., Santafé de Bogotá D.C., Colombia.
"Acne"
W.J.
Cunliffe (1995) p.
IN: Cutaneous Medicine and Surgery Published by Harcourt, Brace & Co. "Non Random Usage of T Cell Receptor α Gene Expression in Atopy Using Anchored PCR" A.H. Mansur, C.M. Gelder, D. Holland, D.A. Campbell, A. Griffin, W. Cunliffe, A.F. Markham and J.F.J.
Morrison (1996) p.381- IN: New Horizons in Allergy Immunotherapy Eds. Sehon et al. Published by Plenum Press, New York. "Non Random Usage of T Cell Receptor α Gene Expression in Atopy Using Anchored PCR" A.H. Mansur, C.M. Gelder, D. Holland, D.A. Campbell, A. Griffin, W. Cunliffe, A.F. Markham and J.F.J.
Morrison (1996) p.381-
IN: New Horizons in Allergy Immunotherapy Eds. Sehon et al. Published by Plenum Press, New York. "Disorders of the Sebaceous Glands" Cunliffe and N.B. Simpson (1998) p.1927-1984
and "Necrobiotic Cunliffe (1998) p.2297-2309
and "Subcutaneous M.M. Black and W.J. Cunliffe (1998) p.2403-2435
IN: Textbook of Dermatology (6th edition) Eds. R.H. Champion, J.L. Burton, D.A. Burns and S.M. Breathnach Published by Blackwell Science Ltd., Oxford.
1999 "Acne"
W.J.
Cunliffe and D.C. Seukeran (1999) p.3-10
IN: European Handbook of Dermatological Treatments Eds. A.D. Katsambas and T.M. Lotti Published by Springer-Verlag, Berlin. "Über die Therapie der komplizierten Akne Vulgaris" S. Sommer and W.J. Cunliffe (2000) p. 250-256
IN: Dermatologie an der Schwelle zum neuen Jahrtausend Eds. A. Plettenberg, W.N. Meigel and I. Moll Published by Springer-Verlag, Berlin.
PRESENTATIONS
National 1960-1997 184 Comparison of the yeast British Society of Saadatzadeh M.R. mycelial antigens of Malassezia Investigative Ashbee Dermatology Cunliffe
Liverpool - April Do patients with less severe British Association acne show an increased side of Dermatologists effect profile when prescribed (Poster) Cunliffe
oral isotretinoin? Treatment of acne fulminans - British Association a review of 25 cases of Dermatolgists Cunliffe
The role of the sebolith in British Association the pathogenesis of inflamed of Dermatologists (Poster) Cunliffe
Are repeat courses of oral British Association isotretinoin safe and effective of Dermatologists Cunliffe
Light cautery of macrocomedones British Association under general anaesthesia of Dermatologists Sheehan-Dare R.A. (Poster) Cunliffe
The changing face of acne 15th Annual Course Cunliffe
for Consultants & 'How to Understand and Manage Rashes' St. John's Institute of Dermatology, London - Infantile acne - a clinical and British Association therapeutic study of Dermatologists Cunliffe
Edinburgh - July Acne fulminans 'sine fulminans' British Association Dermatologists Cunliffe
Edinburgh - July The psychological impact of British Association of Dermatologists Cunliffe
Edinburgh - July Assessment of the psychological British Association and social impact of acne of Dermatologists vulgaris on the adult population (Poster) Cunliffe
Edinburgh - July Psychological and clinical British Association improvement of acne scarring of Dermatologists Cunliffe
following ultrapulse laser Edinburgh - July International 1971-1997 203 The pathological and American Academy of Cunliffe
therapeutic control of A role for interleukin 1α in 3rd Joint Meeting ESDR/Japanese SID/SID Cologne - May Cunliffe
Abnormal integrin expression 3rd Joint Meeting ESDR/Japanese SID/SID Cologne - May Cunliffe
The microbiology of acne Clinical Dermatology Cunliffe
2000 "Acne in the Next Century" Singapore - June War on Comedones Skin Therapy Forum IV Cunliffe
Cardiff - October Treatment of acne fulminans - Skin Therapy Forum IV a review of 25 cases (Poster) Cunliffe
Cardiff - October Lack of absorption of topical Skin Therapy Forum IV isotretinoin alone or in combination with erythromycin Cardiff - October Cunliffe
Human Peripheral Blood 29th Annual Meeting Mononuclear Cell Response European Society Cunliffe
Propionibacterium acnes for Dermatological and heat shock proteins in inflammatory acne vulgaris 8th Congress of the Cunliffe
European Academy of Amsterdam – September 1999 GUEST LECTURES
National and International "The aetiology and treatment of acne" (Salford Postgraduate Centre) "Optimum use of Roaccutane in acne" Dermatological Society) "Optimum use of Roaccutane in acne" "Diagnosis of acne variants" "Comedogenesis - some new aetiological, clinical and therapeutical observations" "Comedogenesis - some new aetiological, clinical and therapeutical observations" "New Developments in the Treatment of Acne" (Frontiers in Dermatology) British Association of Dermatologists "Pilosebaceous (Introductory Course on the Biology of the Skin) Addenbrookes Postgraduate Medical Centre "Acne - How I am treating now - how I will treat (Portugese Dermatology Department) "How to treat difficult acne" (Danish Dermatological Meeting) "Creating an acne free zone" (Dermatology Postgraduate Lecture) "How I manage my difficult acne patients" (German Dermatological Society) "Systemic antibiotics for acne, management, benefits, risks" (9th Journée Européenne d'Echange en Thérapeutique Dermatologique-Acné Polymorphe Juvénile Actualités Thérapeutiques - French Association of Dermatology) "Manchester-An acne free zone by the millennium. Variation on a theme" "Comedogenesis-Mechanism, Clinical Appearance and Treatment" (Lütfü Tat National Dermatology Symposium) "Adapalene-Some new information" (Lütfü Tat National Dermatology Symposium) "The aetiology of acne" (Lütfü Tat National Dermatology Symposium) "The treatment of acne" (Lütfü Tat National Dermatology Symposium) "The treatment of difficult acne" (Lütfü Tat National Dermatology Symposium) "Some Difficult Acne Patients" Dermatological Society) "Yorkshire - An Acne Free Zone by the Millennium" (Dermatology Update, Wharfedale Postgraduate Meeting) "The Difficult Acne Patient" (Buckinghamshire Academic Meeting) (Measuring Skin Disease) Centre for Evidence-Based Pharmacotherapy One-Day "Pilosebaceous (Introductory Course on the Biology of the Skin) Addenbrookes Postgraduate Medical Centre ORATIONS
1975 DOWLING
"Fibrinolysis and Vasculitis" JOHN INGRAM ORATION "A computerised and clinical study of acne therapy" CHAIRMAN - INTERNATIONAL SYMPOSIA
Workshop on Acne (European Society for Dermatological Research) Workshop on Acne (European Society for Dermatological Research) Recent Advances in Acne Dermatological Conference) (European Society for Dermatological Research) 1983 Pharmacological (European Society for Dermatological Research) Acne - A Review (Co-Director) (American Academy of Dermatology) Pathogenesis and Principles in the Treatment of Acne (Co-Director) (American Academy of Dermatology) Keratinocytes/Cell (European Society for Dermatological Research) (Roche Northern European Symposium for Dermatologists) (European Society for Dermatological Research) Pathogenesis and Principles in the Treatment of Acne (American Academy of Dermatology) Acne - What's New? (Forum) (1st Congress of the European Academy of Dermatology (European Society for Dermatological Research/Society for Investigative Dermatology) Pathogenesis and Principles in the Treatment of Acne (American Academy of Dermatology) (European Society for Dermatological Research) (The Environmental Threat to the Skin) Pilosebaceous/Retinoids (European Society for Dermatological Research) (2nd Congress European Academy of Dermatology and (European Society for Dermatological Research) (18th World Congress of Dermatology) New Molecules for Old Diseases (Skin Therapy Forum - A Future Look) Acne - its prevention and cure by the year 2000 Acne in the 21st Century (Clinical Dermatology 2000) Skin, Sexual Hormones and Acne (7th Congress European Academy of Dermatology and (8th Congress European Academy of Dermatology and CHAIRMAN - POSTER AWARDS
European Society for Dermatological Research European Society for Dermatological Research World Congress of Dermatology 1st Congress of the European Academy of Dermatology 2nd Congress European Academy of Dermatology and 3rd Congress of the European Academy of Dermatology 8th Congress of the European Academy of Dermatology LEARNED JOURNAL COMMITMENTS
Reviewer of papers for: British Medical Journal British Journal of Dermatology Journal of Investigative Dermatology Clinical Science Archives of Dermatology American Academy Journal of Dermatology Acta Dermatovenerol (Stock.) Editorial Board Member of: Clinical & Experimental Dermatology Dermatology in Practice (Editor) Journal of Dermatological Treatment Dermatology (formerly Dermatologica) The Journal of Clinical Dermatology Current Medical Literature-Dermatology Acta Dermato-Venereologica COMMITTEE ACTIVITIES
National and International Committee Member - Leeds Medical Sciences Club Secretary - Leeds Medical Sciences Club Committee Member - Skin Club, London Committee Member - The North of England Dermatological Society Committee Member - British Association of Dermatologists (Investigative Group) Organising Local Secretary - British Association of Dermatologists (Investigative Group) Chairman - British Association of Dermatologists (Investigative Group) Committee Member - British Association of Dermatologists (Executive Committee) Educational Sub-Committee - British Association of Secretary - Skin Club, London U.K. Representative - European Society for Dermatological Research Committee Secretary - European Society for Dermatological Research President - European Society for Dermatological Research Vice-Chairman - Yorkshire Regional Dermatologists Committee Member - British Association of Dermatologists Therapy Sub-Group Chairman - Yorkshire Regional Dermatologist Chairman - British Association of Dermatologists Therapy 18. Member - International Scientific Committee, European Academy of Dermatology and Venereology Committee Member - British Skin Foundation HONORARY MEMBERSHIP OF OVERSEAS SOCIETIES
French Dermatological Society Greek Dermatological Society Swedish Dermatological Society Finnish Dermatological Society American Academy of Dermatology American Dermatological Association Deutsche Dermatologische Gessellschaft SUPERVISION OF HIGHER DEGREES
The following people have been successful in obtaining Higher Degrees either under mine or joint supervision. 1. Dr. J.A. Cotterill (M.D.) 1972 "Surface Lipid Composition of Control Subjects and Subjects with Acne" Dr. S.G. Tan (M.D.) 1975 "A Laboratory and Clinical Study with Special Reference to Microbial Factors Pathogenesis" Dr. C.D. Roberts (Ph.D.) 1975 "The Role of Bacteria in Acne Vulgaris" Dr. B. Dodman (M.D.) 1977 "Fibrinolytic Activity in Cutaneous Vasculitis" Dr. E.A. Eady (Ph.D.) 1979 "Antimicrobiosis by Members of the Resident Bacterial Flora of Normal and Dr. E. Ingham (Ph.D.) 1979 "An Investigation of Propionibacterium Acnes Exocellular Enzymes" Dr. D. Blanc (M.D.) 1979 "Acne Vulgaris - A Clinical Study" Dr. N.B. Simpson (M.D.) 1980 "Sebaceous Gland Hormones" Dr. P. Bladon (Ph.D.) 1983 "Fibrous Protein Synthesis in Normal and Disease" K. King (M.Phil.) 1983 "A Study of Pathogenetic Mechanisms in Acne" Dr. J. Leeming (Ph.D.) 1984 "The Microbial Flora of the Pilosebaceous Duct" Dr. H.A.M. Albaghdadi (Ph.D.) 1985 "The Structure and Function of the Skin in relation to Acne Vulgaris" Dr. D.H. Jones (M.D.) 1987 "A Clinical and Laboratory Study of the Effect of 13-cis Retinoic Acid in Dr. J.K. McMorris (Ph.D.) 1987 "Investigation of the Role of Cellular Retinoid-Binding Proteins in Human Dr. R. Bojar (Ph.D.) 1990 "The In Vitro Antimicrobial Effects of Azelaic Acid upon Cutaneous Microorganisms" Dr. J. Ross (Ph.D.) 1990 "Characterization of a Macrolide-Streptogranin B Resistance Determined from Coagulase-Negative Staphylococci" Dr. P.J. Rowling (Ph.D.) 1990 "Investigation of Potentialities of Skin Equivalents Suitable for Grafting of Burn Wounds" Dr. E.M. Gribbon (Ph.D.) 1991 "Interaction of Propionibacterium Acnes with Skin Lipids" Dr. B.R. Hughes (M.D.) 1992 "The Structure and Function of the Pilosebaceous Duct in Health and Disease with Special Reference to Acne Vulgaris" Dr. H.E. Knaggs (Ph.D.) 1992 "Studies on the Biochemistry and Physiology of the Pilosebaceous Duct in Health and Disease" Dr. H.R. Ashbee (Ph.D.) 1993 "The Role of Malassezia in Dermatoses" Dr. J.L. Tipper (Ph.D.) 1994 "Erythromycin Resistance in Cutaneous Propionibacteria and Staphylococci" Dr. K.J. Gardner (Ph.D.) 1995 "Acne, its Assessment and Pharmacological Manipulation" Dr. O.L. Aldana (Ph.D.) 1998 "The Initiation and Resolution of Acne: A Pharmacological Approach" Dr. C.H. McGeown (Ph.D.) 1998 "The Physiology and Immunocytochemitry of Post-Adolescent Acne" Dr. C.E. Walters (Ph.D.) 1998 "The Effects of Erythromycin on Adhesion Molecules and Inflammatory Markers In Vitro" I have been the Supervisor for 5 B.Sc. Pharmacology students over the last 10 years. I am currently supervising the following Degrees: S. Macdonald Hull (M.D.) A. Layton (M.D.) A. Jeremy (Ph.D.)

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Pharmaceutical Law & Industry Report® Reproduced with permission from Pharmaceutical Law & Industry Report, 12 PLIR 41, 10/17/2014. Copyright 姝2014 by The Bureau of National Affairs, Inc. (800-372-1033) http://www.bna.com Manufacturing Trouble: Is cGMP the Next Enforcement Frontier? BY EMILY R. SCHULMAN, MICHAEL J. BAYER AND departments are, by now, quite familiar. But many com-panies view cGMP issues through a regulatory prism,

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Supplementary materials LANTERN: a randomized study of QVA149 versus salmeterol/fluticasone combination in patients with COPD Nanshan Zhong 1, Changzheng Wang2, Xiangdong Zhou3, Nuofu Zhang1, Michael Humphries4, Linda Wang4, Chau Thach5, Francesco Patalano6, Donald Banerji5, for the LANTERN Investigators* METHODS (ADDITONAL DETAILS)