Chester Clinic

 

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SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 Date of issue: 13.08.2015 SECTION 1. Identification of the substance/mixture and of the company/undertaking 1.1 Product identifier RonaCare® Caffeine REACH Registration Number A registration number is not available for this substance as the substance or its use are exempted from registration according to Article 2 REACH Regulation (EC) No 1907/2006, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline. 1.2 Relevant identified uses of the substance or mixture and uses advised against Cosmetic raw material For additional information on uses please refer to the Merck Chemicals portal (www.merckgroup.com). 1.3 Details of the supplier of the safety data sheet Merck KGaA * 64271 Darmstadt * Germany * Tel: +49 6151 72-0 Responsible Department [email protected] Regional representation Merck Pty Ltd. * South Africa * 259 Davidson Road, Corner Peddie Road, Wadevil e, Germiston 1428 * Tel. +27 (0) 8600 63725 * Fax: +27 (0) 860 522 329 1.4 Emergency telephone Mobile + 27 82 562 5923 SECTION 2. Hazards identification 2.1 Classification of the substance or mixture Classification (REGULATION (EC) No 1272/2008) Acute toxicity, Category 4, Oral, H302 For the full text of the H-Statements mentioned in this Section, see Section 16. Classification (67/548/EEC or 1999/45/EC) For the full text of the R-phrases mentioned in this Section, see Section 16. 2.2 Label elements Labelling (REGULATION (EC) No 1272/2008) Hazard pictograms The Safety Data Sheets for catalogue items are available at www.merckgroup.com SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 RonaCare® Caffeine Hazard statements H302 Harmful if swal owed. Reduced labelling (≤125 ml) Hazard pictograms 2.3 Other hazards SECTION 3. Composition/information on ingredients C₈H₁₀N₄O₂ (Hil ) Hazardous components (REGULATION (EC) No 1272/2008) Chemical Name (Concentration) Registration number Caffeine (<= 100 % ) Acute toxicity, Category 4, H302 *) A registration number is not available for this substance as the substance or its use are exempted from registration according to Article 2 REACH Regulation (EC) No 1907/2006, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline. For the full text of the H-Statements mentioned in this Section, see Section 16. Hazardous components (1999/45/EC) Chemical Name (Concentration) Caffeine (<= 100 % ) Xn, Harmful; R22 For the full text of the R-phrases mentioned in this Section, see Section 16. SECTION 4. First aid measures 4.1 Description of first aid measures After inhalation: fresh air. The Safety Data Sheets for catalogue items are available at www.merckgroup.com SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 RonaCare® Caffeine In case of skin contact: Take off immediately al contaminated clothing. Rinse skin with water/ shower. After eye contact: rinse out with plenty of water. After swal owing: immediately make victim drink water (two glasses at most). Consult a 4.2 Most important symptoms and effects, both acute and delayed agitation, Diarrhoea, Vomiting, col apse, Headache, restlessness 4.3 Indication of any immediate medical attention and special treatment needed Subsequently administer: activated charcoal (20 - 40 g in 10% slurry). SECTION 5. Firefighting measures 5.1 Extinguishing media Suitable extinguishing media Water, Carbon dioxide (CO2), Foam, Dry powder Unsuitable extinguishing media For this substance/mixture no limitations of extinguishing agents are given. 5.2 Special hazards arising from the substance or mixture Risk of dust explosion. Development of hazardous combustion gases or vapours possible in the event of fire. Fire may cause evolution of: 5.3 Advice for firefighters Special protective equipment for firefighters Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing. Further information Suppress (knock down) gases/vapours/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system. SECTION 6. Accidental release measures 6.1 Personal precautions, protective equipment and emergency procedures Advice for non-emergency personnel: Avoid substance contact. Avoid inhalation of dusts. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: Protective equipment see section 8. 6.2 Environmental precautions Do not empty into drains. 6.3 Methods and materials for containment and cleaning up Cover drains. Col ect, bind, and pump off spil s. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts. 6.4 Reference to other sections The Safety Data Sheets for catalogue items are available at www.merckgroup.com SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 RonaCare® Caffeine Indications about waste treatment see section 13. SECTION 7. Handling and storage 7.1 Precautions for safe handling Advice on safe handling Observe label precautions. Hygiene measures Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance. 7.2 Conditions for safe storage, including any incompatibilities Storage conditions Tightly closed. Dry. Recommended storage temperature see product label. 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated. SECTION 8. Exposure controls/personal protection 8.1 Control parameters Contains no substances with occupational exposure limit values. 8.2 Exposure controls Engineering measures Technical measures and appropriate working operations should be given priority over the use of personal protective equipment. See section 7.1. Individual protection measures Protective clothing needs to be selected specifical y for the workplace, depending on concentrations and quantities of the hazardous substances handled. The chemical resistance of the protective equipment should be enquired at the respective supplier. Eye/face protection Safety glasses Hand protectionfull contact: Glove thickness: Break through time: Glove thickness: Break through time: The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374, for example KCL 741 Dermatril® L (full contact), KCL 741 Dermatril® L (splash contact). The breakthrough times stated above were determined by KCL in laboratory tests acc. to EN374 with samples of the recommended glove types. The Safety Data Sheets for catalogue items are available at www.merckgroup.com SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 RonaCare® Caffeine This recommendation applies only to the product stated in the safety data sheet<(>,<)> supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Other protective equipment protective clothing Respiratory protection required when dusts are generated. Recommended Filter type: Filter P 1 (acc. to DIN 3181) for solid particles of inert substances The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. Environmental exposure controls Do not empty into drains. SECTION 9. Physical and chemical properties 9.1 Information on basic physical and chemical properties Boiling point/boiling range Evaporation rate No information available. Flammability (solid, gas) May form combustible dust concentrations in air Lower explosion limit No information available. Upper explosion limit No information available. Relative vapour density No information available. The Safety Data Sheets for catalogue items are available at www.merckgroup.com SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 RonaCare® Caffeine Relative density No information available. Water solubility Partition coefficient: n- log Pow: -0.09 (23 °C) Bioaccumulation is not expected. (Lit.) Auto-ignition temperature No information available. Decomposition temperature No information available. Viscosity, dynamic No information available. Explosive properties Not classified as explosive. Oxidizing properties Sublimation point Ignition temperature Method: DIN 51794 SECTION 10. Stability and reactivity Risk of dust explosion. 10.2 Chemical stability 10.3 Possibility of hazardous reactions Violent reactions possible with: Strong oxidizing agents 10.4 Conditions to avoid 10.5 Incompatible materials no information available 10.6 Hazardous decomposition products in the event of fire: See section 5. The Safety Data Sheets for catalogue items are available at www.merckgroup.com SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 RonaCare® Caffeine SECTION 11. Toxicological information 11.1 Information on toxicological effects Acute oral toxicity LD50 Rat: 367.7 mg/kg OECD Test Guideline 401 Acute inhalation toxicity This information is not available. Acute dermal toxicity LD50 Rat: > 2,000 mg/kg OECD Test Guideline 402 Result: No irritation OECD Test Guideline 404 Result: No eye irritation OECD Test Guideline 405 In animal experiments: Mouse Result: Does not cause skin sensitisation. Method: OECD Test Guideline 429 Germ cell mutagenicity Genotoxicity in vitro In vitro mammalian cel gene mutation test Mouse lymphoma test Result: negative Method: OECD Test Guideline 476 Salmonel a typhimurium Result: negative This information is not available. Reproductive toxicity This information is not available. This information is not available. Specific target organ toxicity - single exposure This information is not available. Specific target organ toxicity - repeated exposure This information is not available. The Safety Data Sheets for catalogue items are available at www.merckgroup.com SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 RonaCare® Caffeine Aspiration hazard This information is not available. 11.2 Further information After absorption of toxic quantities: Diarrhoea, Vomiting, agitation, restlessness, Headache Systemic effects: drop in blood pressure, tachycardia, col apse Handle in accordance with good industrial hygiene and safety practice. SECTION 12. Ecological information LC50 Leuciscus idus (Golden orfe): ca. 87 mg/l; 96 h DIN 38412 part 15 NOEC Leuciscus idus (Golden orfe): 46 mg/l; 96 h DIN 38412 part 15 Toxicity to daphnia and other aquatic invertebrates static test EC50 Daphnia magna (Water flea): 182 mg/l; 48 h Toxicity to algae EC50 Desmodesmus subspicatus (green algae): > 100 mg/l; 72 h OECD Test Guideline 201 NOEC Desmodesmus subspicatus (green algae): 6.25 mg/l; 72 h OECD Test Guideline 201 Toxicity to bacteria BRINGMANN-KüHN-TEST EC50 Pseudomonas putida: 3,490 mg/l; 17 h EC50 activated sludge: > 1,000 mg/l; 3 h OECD Test Guideline 209 12.2 Persistence and degradability OECD Test Guideline 301A Readily biodegradable 12.3 Bioaccumulative potential Partition coefficient: n-octanol/water log Pow: -0.09 (23 °C) Bioaccumulation is not expected. (Lit.) 12.4 Mobility in soil No information available. 12.5 Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted. 12.6 Other adverse effects Additional ecological information Discharge into the environment must be avoided. The Safety Data Sheets for catalogue items are available at www.merckgroup.com SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 RonaCare® Caffeine SECTION 13. Disposal considerations Waste treatment methods Waste material must be disposed of in accordance with the national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself. See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions. SECTION 14. Transport information Land transport (ADR/RID)14.1 - 14.6 Not classified as dangerous in the meaning of transport Inland waterway transport (ADN) Not relevant Air transport (IATA)14.1 - 14.6 Not classified as dangerous in the meaning of transport Sea transport (IMDG)14.1 - 14.6 Not classified as dangerous in the meaning of transport 14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code SECTION 15. Regulatory information 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture National legislation Dust explosion class 15.2 Chemical Safety Assessment For this product a chemical safety assessment was not carried out. SECTION 16. Other information Merck (company-internal/in-house) Occupational Exposure Limit (Merck OEL) Internal company value Short Term Exposure (15 min) Factor Pregnancy risk groups C There is no reason to fear damage to the embryo, or foetus when the Merck OEL value is observed. The Safety Data Sheets for catalogue items are available at www.merckgroup.com SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 RonaCare® Caffeine Ful text of H-Statements referred to under sections 2 and 3. H302 Harmful if swallowed. Ful text of R-phrases referred to under sections 2 and 3 R22 Harmful if swallowed. Training advice Provide adequate information, instruction and training for operators. Hazard pictograms Hazard statements H302 Harmful if swal owed. Labelling (67/548/EEC or 1999/45/EC)Symbol(s) Harmful if swallowed. Key or legend to abbreviations and acronyms used in the safety data sheet Used abbreviations and acronyms can be looked up at www.wikipedia.org. The information contained herein is based on the present state of our knowledge. It characterises the product with regard to the appropriate safety precautions. It does not represent a guarantee of any properties of the product.
The Safety Data Sheets for catalogue items are available at www.merckgroup.com

Source: http://www.merck-performance-materials.de/merck-ppf/detailRequest?unit=CHEM&owner=MDA&productNo=132284&language=EN&country=ZA&docType=MSD&source=SAPHIR&docId=EN;ZA