Important safety information:
DEPAKOTE SAVINGS PROGRAM
DEPAKOTE SAVINGS PROGRAM
Pay as little as
BILL PRIMARY INSURANCE FIRST
INSURED PATIENTS ONLY
*Up to $75 off for eligible insured patients.
See brochure for Important Safety Information, including
Go to GetDepakote.com to sign
warnings for risk of liver problems, pancreas problems,
and birth defects. See full Prescribing Information in pocket. up for monthly refill reminders.
Start Saving Today.*
* See eligibility restrictions below.
Take this printout with your prescription for Depakote, Depakote ER, or Depakote Sprinkle Capsules
to your pharmacist and start saving immediately!
Present this printed Co-Pay Card every time you fill a Depakote, Depakote ER, or Depakote Sprinkle
Capsules prescription for instant savings. This card can be used up to 2 times per month.
You pay the first $5 of your co-payment on qualified prescriptions, and the discount covers up to the
next $75 off of your remaining co-pay expenses. The card is valid at mail-order pharmacies, but they may
have different requirements. If needed, you can find a rebate form on Depakote.com.
✓ When filling a prescription for Depakote, Depakote ER, or Depakote Sprinkle Capsules, make sure
your pills look like those shown below. If not, call your doctor or talk to your pharmacist.
Depakote 125 mg Depakote 250 mg Depakote 500 mg
Depakote ER 250 mg Depakote ER 500 mg
Depakote Sprinkle Capsules 125 mg
Tablets and Capsule Shown Are Not Actual Size
✓ Inform your pharmacist of your preference for the Depakote brand.
✓ Check the label on your prescription bottle to be sure it says Depakote, Depakote ER, or
Depakote Sprinkle Capsules.
Present this printable version of the Depakote, Depakote ER, or Depakote Sprinkle Capsules Co-Pay Card along with your insurance card when presenting your
prescription in order to receive discounts. You pay the first $5 of your co-payment on qualified prescriptions and the discount covers up to the next $75 off of your
remaining co-pay expenses. This printout is valid for up to 2 uses per month. This is also valid at mail-order pharmacies, yet they may have different requirements.
Please contact your mail-order pharmacist for redemption instructions.
Please submit the co-pay authorized by the patient's primary insurance as a secondary transaction
to OPUS Health. If you have questions, please call OPUS Health at: 1-800-364-4767.
This offer may be changed or discontinued without notice.
This downloadable discount is the property of AbbVie Inc. and must be surrendered upon demand. Offer not valid in Massachusetts. Available to patients with commercial prescription insurance coverage for
Depakote. Co-pay assistance program is not available to patients receiving prescription reimbursement under
any federal, state or government-funded insurance programs (for example, Medicare, Medicaid, TRICARE,
Department of Defense or Veteran's Affairs programs) or where prohibited by law. Offer subject to change or
discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not
Please read Uses and Important Safety Information, including risks of
liver problems, pancreas problems, and birth defects on the next page.
Full Prescribing Information available at
What is Depakote used for?1-3
Depakote comes in different dosage forms. Depakote® (divalproex sodium) tablets, for oral use, and
Depakote® ER (divalproex sodium) extended-release tablets, for oral use, are prescription medications used:
• to treat manic episodes associated with bipolar disorder
• alone or with other medicines to treat:
– complex partial seizures in adults and children 10 years of age and older
– simple and complex absence seizures, with or without other seizure types
• to prevent migraine headaches
Depakote® Sprinkle Capsules (divalproex sodium delayed release capsules), for oral use, is a prescription medicine used alone or with other medicines to treat: • complex partial seizures in adults and children 10 years of age and older • simple and complex absence seizures, with or without other seizure types
Important Safety Information1-3
The most important information about Depakote is:
Do not stop taking Depakote without first talking to your healthcare provider. Stopping Depakote suddenly can cause
Depakote can cause serious side effects, including:
• Serious liver damage that can cause death, especially in children younger than 2 years old. The risk of getting this
serious liver damage is more likely to happen within the first 6 months of treatment. In some cases, liver damage may
continue despite stopping the drug. Call your healthcare provider right away if you get any of the following symptoms:
nausea or vomiting that does not go away, loss of appetite, pain on the right side of your stomach (abdomen), dark urine,
swelling of your face, or yellowing of your skin or the whites of your eyes.
• Depakote may harm your unborn baby. If you take Depakote during pregnancy for any medical condition, your baby is
at risk for serious birth defects that affect the brain and spinal cord and are called spina bifida or neural tube defects. These
defects occur in 1 to 2 out of every 100 babies born to mothers who use this medicine during pregnancy. These defects can
begin in the first month, even before you know you are pregnant. Other birth defects that affect the structures of the heart,
head, arms, legs, and the opening where the urine comes out (urethra) on the bottom of the penis can also happen. Birth
defects may occur even in children born to women who are not taking any medicines and do not have other risk factors.
Taking folic acid supplements before getting pregnant and during early pregnancy can lower the chance of having a baby
with a neural tube defect. If you take Depakote during pregnancy for any medical condition, your child is at risk for having a
lower IQ. There may be other medicines to treat your condition that have a lower chance of causing birth defects and
decreased IQ in your child. Women who are pregnant must not take Depakote to prevent migraine headaches. All women of
childbearing age should talk to their healthcare provider about using other possible treatments instead of Depakote.
If the decision is made to use Depakote, you should use effective birth control (contraception). Tell your healthcare
provider right away if you become pregnant while taking Depakote. You and your healthcare provider should decide if you will
continue to take Depakote while you are pregnant. Pregnancy Registry: If you become pregnant while taking Depakote,
talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. You can
enroll in this registry by calling 1-888-233-2334. The purpose of this registry is to collect information about the safety of
antiepileptic drugs during pregnancy.
• Inflammation of your pancreas that can cause death. Call your healthcare provider right away if you have any of
these symptoms: severe stomach pain that you may also feel in your back, nausea or vomiting that does not go away.
• Like other antiepileptic drugs, Depakote may cause suicidal thoughts or actions in a very small number of people,
about 1 in 500. Call a healthcare provider right away if you have any of these symptoms, especially if they are new,
worse, or worry you: thoughts about suicide or dying; attempts to commit suicide; new or worse depression; new or worse
anxiety; feeling agitated or restless; panic attacks; trouble sleeping (insomnia); new or worse irritability; acting aggressive,
being angry, or violent; acting on dangerous impulses; an extreme increase in activity and talking (mania); other unusual
changes in behavior or mood.
Do not take Depakote if you:
• have liver problems
• have or think you have a genetic liver problem caused by a mitochondrial disorder (e.g., Alpers Huttenlocher Syndrome)
• are allergic to divalproex sodium, valproic acid, sodium valproate, or any of the ingredients in Depakote
• have a genetic problem called urea cycle disorder
• are pregnant and taking Depakote for the prevention of migraine headaches
Before taking Depakote, tell your healthcare provider if you:
• have a genetic liver problem caused by a mitochondrial disorder (e.g., Alpers Huttenlocher Syndrome)
• drink alcohol
• are pregnant or breastfeeding since Depakote can pass into breast milk. Ask your healthcare provider about the best way
to feed your baby.
• have or have had depression, mood problems, or suicidal thoughts or behavior • have any other medical condition
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines,
vitamins, herbal supplements.
Taking Depakote with certain other medicines, even for a short period of time, can cause side effects or affect how well they work. Do not start or stop other medicines without talking to your healthcare provider.
Depakote can cause other serious side effects, including:
• Bleeding problems: red or purple spots on your skin, bruising, pain and swelling into your joints due to bleeding or
bleeding from your mouth or nose.
• High ammonia levels in your blood: feeling tired, vomiting, changes in mental status.
• Low body temperature (hypothermia): drop in your body temperature to less than 95º F, feeling tired, confusion, coma.
• Allergic (hypersensitivity) reactions: fever, skin rash, hives, sores in your mouth, blistering and peeling of your skin,
swelling of your lymph nodes, swelling of your face, eyes, lips, tongue, or throat, trouble swallowing or breathing.
• Drowsiness or sleepiness in the elderly. This extreme drowsiness may cause you to eat or drink less than you
normally would. Tell your doctor if you are not able to eat or drink as you normally do. Your doctor may start you at a lower dose of Depakote.
Common side effects of Depakote include:
• double vision
• problems with
• weakness • stomach pain
• sleepiness • tremor
• blurry vision
• increased appetite • loss of appetite
Please see the full Prescribing Information, including Medication Guide, for additional information about Depakote. Talk
to your healthcare provider if you have questions.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you cannot afford your medication, contact: www.pparx.org for assistance.
1. Depakote [package insert].
2. Depakote ER [package insert].
3. Depakote Sprinkle Capsules [package insert].
2015 AbbVie Inc. North Chicago, IL 60064 1906086-1797913 July 2015
DEPAKOTE SAVINGS PROGRAM DEPAKOTE SAVINGS PROGRAM Pay as little as BILL PRIMARY INSURANCE FIRST INSURED PATIENTS ONLY *Up to $75 off for eligible insured patients. See brochure for Important Safety Information, including Go to GetDepakote.com to sign warnings for risk of liver problems, pancreas problems, and birth defects. See full Prescribing Information in pocket. up for monthly refill reminders.
Willdenowia 42 – 2012 Filip VerlooVe1 & enrique Sánchez Gullón2 A taxonomic revision of non-native Cenchrus s.str. (Paniceae, Poaceae) in the Medi-terranean area AbstractVerloove F. & Sánchez Gullón e.: A taxonomic revision of non-native Cenchrus s.str. (Paniceae, Poaceae) in the Mediterranean area. – Willdenowia 42: 67 – 75. June 2012. – online iSSn 1868-6397; © 2012 BGBM Berlin-Dahlem.