Ogni antibiotico è efficace in relazione a un determinato gruppo di microrganismi comprare amoxil senza ricettain caso di infezioni oculari vengono scelte gocce ed unguenti.

Microsoft word - effectmicrotechcs_sds_en_19012012.doc

UNICHEM d.o.o.
SAFETY DATA SHEET
Date of compilation: Sinja Gorica 2, 1360 Vrhnika Tel: 01/7558-150Fax: 01/7558-155 EFFECT MICROTECH CS
Revision: 19.01.2012 Version no.: 001
SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1. Product identifier:
EFFECT MICROTECH CS 1.2. Relevant identified uses of the substance or mixture and uses advised against:
Insecticide (microencapsulated concentrate) for professional use against crawling insects such as ants
and cockroaches.

Uses advised against: use only for intentions listed in this safety data sheet or on product label.
Any other use is forbidden.

1.3. Details of the supplier of the safety data sheet:
UNICHEM d.o.o., Sinja Gorica 2, 1360 Vrhnika, Slowenien Telephone: +386 (01) 75 58 150, fax: +386 (01) 75 58 155
E-Mail address for a competent person responsible for the safety data sheet:
marko.devetak@unichem.si

1.4
. Emergency telephone number:
Consult a personal or emergency physician. In case of a life endangerment call 112. Information about the emergency measures: tel.: +386 (01) 75 58 150, fax: +386 (01) 75 58 155 (from 7:00 to 15:00)



UNICHEM d.o.o.
SAFETY DATA SHEET
Date of compilation: Sinja Gorica 2, 1360 Vrhnika Tel: 01/7558-150Fax: 01/7558-155 EFFECT MICROTECH CS
Revision: 19.01.2012 Version no.: 001 SECTION 2: Hazards identification

2.1. Classification of the substance or mixture:
Classification of the substance/ mixture according to Directive 67/548/EEC and 1999/45/EG:

N - Dangerous for the environment R20/22 Harmful by inhalation and if swallowed. R43 May cause sensitization by skin contact. R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
2.2. Label elements:
According to Directive 67/548/EEC and 1999/45/EG:
Dangerous for Harmful
the environment

R20/22 Harmful by inhalation and if swallowed. R43 May cause sensitization by skin contact. R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. S2 Keep out of the reach of children. S13 Keep away from food, drink and animal feeding stuffs. S24/25 Avoid contact with skin and eyes. R36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S60 This material and its container must be disposed of as hazardous waste. S61 Avoid release to the environment. Refer to special instructions/Safety data sheets. Other information: Contents: Permethrin (ISO), tetramethrin For use only by professional operators. Avoid excessive contamination of coveralls. Do not contaminate foodstuffs, eating utensils or food contact surfaces. Wash hands and exposed skin before meals and after use. Keep in a safe place. Remove or cover all fish tanks and bowls before application. Unprotected persons and animals should be kept away from treated areas until surfaces are dry. Cover all water storage tanks before application. Hazardous to bees. Do not apply to clothing and bedding. All bats are protected under the Wildlife and Countryside Act 1981. Before treating any structure used by bats, consult Natural England, Scottish Natural Heritage or the Conntryside Council for Wales. 2.3. Other hazards:

No other hazards. UNICHEM d.o.o.
SAFETY DATA SHEET
Date of compilation: Sinja Gorica 2, 1360 Vrhnika Tel: 01/7558-150Fax: 01/7558-155 EFFECT MICROTECH CS
Revision: 19.01.2012 Version no.: 001
SECTION 3: Composition/information on ingredients
3.1. Mixtures:

Name of the substance
according to
according to Directive
Index No.
Regulation (EC) No
67/548/EEC
1272/2008
Permethrin (ISO) Acute Tox. 4, H332 Xn, N; R20/22-43- Acute Tox. 4, H302 Skin Sens. 1, H317 Aquatic Acute 1, H400 Aquatic Chronic 1, H410 Aquatic Acute 1, propylpiperonyl ether Aquatic Chronic 1, H410 Aquatic Acute 1, Aquatic Chronic 1, H410
Additional information:
Full text of R-, H- phrases: see section 16.

SECTION 4: First aid measures

4.1. Description of first aid measures:

Inhalation:
Take affected persons out into the fresh air. Seek medical attention if symptoms persist.
Skin contact:
Take off contaminated clothing. Immediately wash with water and soap and rinse thoroughly. Seek
medical advice.
Eye contact:
Rinse opened eye for several minutes under running water. Seek medical attention if symptoms
persist.
Ingestion:
Rinse out mouth with water. Do not induce vomiting. Never give anything by mouth to affected person.
Keep patient warm at rest. Seek medical advice immediately.
UNICHEM d.o.o.
SAFETY DATA SHEET
Date of compilation: Sinja Gorica 2, 1360 Vrhnika Tel: 01/7558-150Fax: 01/7558-155 EFFECT MICROTECH CS
Revision: 19.01.2012 Version no.: 001

4.2. Most important symptoms and effects, both acute and delayed:

In the case of permethrin poisoning can occur hyperactivity, convulsions, paralysis and respiratory arrest. 4.3. Indication of any immediate medical attention and special treatment needed:
Symptomatic treatment.
General advice:

If in doubt, or when symptoms persist, seek medical attention. Never give anything by mouth to an unconscious person.

SECTION 5: Firefighting measures
5.1. Extinguishing media:

Suitable extinguishing media:
Carbon dioxide (CO2).
Dry chemical powder.
Water fog.
Alcohol resistant foam.
Unsuitable extinguishing media:
Water jet.
5.2. Special hazards arising from the substance or mixture:
In case of fire, the product emits toxic and irritating fumes. 5.3. Advice for firefighters:
Wear suitable protective equipment including self-contained breathing apparatus. Do not allow run-off from fire fighting to enter drains or water courses. Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1. Personal precautions, protective equipment and emergency procedures:

Refer to protective measures listed in sections 7 and 8. Use personal protective equipment.
6.2. Environmental precautions:
Do not flush into surface water or sanitary sewer system. If he product contaminates rivers and lakes or drains inform respective authorities.
6.3. Methods and material for containment and cleaning up:

Absorb with liquid-binding material (sand, earth, diatomite) and collect into labeled containers for disposal. Contaminated areas wash with water. Contaminated residues dispose according to recommendations given in section 13. UNICHEM d.o.o.
SAFETY DATA SHEET
Date of compilation: Sinja Gorica 2, 1360 Vrhnika Tel: 01/7558-150Fax: 01/7558-155 EFFECT MICROTECH CS
Revision: 19.01.2012 Version no.: 001

6.4. Reference to other sections:

Protective equipment and clothing - see section 8. Disposal of waste - see section 13.
SECTION 7: Handling and storage
7.1. Precautions for safe handling:

Always use good personal hygiene procedures when handling chemicals. Ensure good ventilation. Use local ventilation at the source of formation of vapours. Eating, drinking, smoking, as well as food-storage, is prohibited in work-room. Wash hands before breaks and at end of work. Observe directions on label and instruction for use. 7.2. Conditions for safe storage, including any incompatibilities:
Store in original container. Keep containers tightly closed in a dry, cool and well-ventilated place. Keep out of the reach of children. Keep away from food, drink and animal feeding stuffs. 7.3. Specific end use(s):
Insecticide use against crawling insects.

SECTION 8: Exposure controls/personal protection

8.1. Control parameters:
8.2. Exposure controls:

8.2.1. Appropriate engineering controls:
Ensure good ventilation. 8.2.2. Individual protection measures, such as personal protective equipment:
Eye/face protection:
Tightly fitting protective goggles with side protection (EN 166).
Skin protection:
Wear suitable glows, solvent resistant. Wear suitable cloth.
Respiratory protection:
Use local ventilation at the source of formation of vapours. Wear personal respiratory protection with
filter for organic vapours (EN149 FFP2S).
Thermal hazards:
Not applicable.
8.2.3. Environmental exposure controls:
Avoid release to the environment. UNICHEM d.o.o.
SAFETY DATA SHEET
Date of compilation: Sinja Gorica 2, 1360 Vrhnika Tel: 01/7558-150Fax: 01/7558-155 EFFECT MICROTECH CS
Revision: 19.01.2012 Version no.: 001
SECTION 9: Physical and chemical properties
9.1. Information on basic physical and chemical properties

Odour threshold: No data available No data available Melting point/freezing point: No data available Initial boiling point/boiling range: No data available No data available Evaporation rate: No data available Flammability (solid, gas): No data available Upper/lower flammability or explosive limits: No data available Vapour pressure: No data available No data available Relative density: Solubility(ies): Miscible with water Partition coefficient: n-octanol/water: No data available Auto-ignition temperature: No data available Decomposition temperature: No data available No data available Explosive properties: No data available Oxidising properties: No data available
9.2. Other information:

No other information. UNICHEM d.o.o.
SAFETY DATA SHEET
Date of compilation: Sinja Gorica 2, 1360 Vrhnika Tel: 01/7558-150Fax: 01/7558-155 EFFECT MICROTECH CS
Revision: 19.01.2012 Version no.: 001
SECTION 10: Stability and reactivity

10.1. Reactivity:
No data available. 10.2. Chemical stability:
The product is stable in normal conditions of use and storage. 10.3. Possibility of hazardous reactions:
No data available. 10.4. Conditions to avoid:
High temperature and fire. 10.5. Incompatible materials:
Strong oxidizers. 10.6. Hazardous decomposition products:
In the event of thermal decomposition or fire, vapours potentially dangerous to health may be released.
SECTION 11: Toxicological information
11.1. Information on toxicological effects:
Permethrin (ISO):
LD50 (oral, Rat): >2000 mg/kg
LD50 (dermal, Rat): >2000 mg/kg
LC50 (inhalation, Rat): >0,45 mg/L
Tetramethrin:
LD50 (oral, Rat): >2000 mg/kg
LD50 (dermal, Rat): >2000 mg/kg
LC50 (inhalation, Rat): >5,63 mg/L
2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether:
LD50 (oral, Rat): 4570 mg/kg
LD50 (dermal, Rat): >2000 mg/kg
LC50 (inhalation, Rat): >5,9 mg/L (4h)
Primary irritant effect: No irritant effect.
Sensitization: May cause sensitization by skin contact.


UNICHEM d.o.o.
SAFETY DATA SHEET
Date of compilation: Sinja Gorica 2, 1360 Vrhnika Tel: 01/7558-150Fax: 01/7558-155 EFFECT MICROTECH CS
Revision: 19.01.2012 Version no.: 001
SECTION 12: Ecological information
12.1. Toxicity:

Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Permethrin (ISO): LC50 (96 h, Guppy, Poecilia reticulata): 8,9 µg/L LC50 (96h, Common Carp, Cyprinus carpio): 0,145 mg/L EC50 (24 h, Daphnia magna): 0,020 mg/L EC50 (72 h, Scenedesmus subspicatus): > 0,022 mg/L EC50 (3 h, Activated sewage sludge): > 1000 mg/L LC50 (Acute toxicity Earthworm, Lampito mauritii): > 1200 mg/kg Tetramethrin: EC50 (48 h) (Daphnia magna): 0,47 mg/l IC50 (72 h) (Scenedesmus subspicatus): > 1,36 mg/l LC50 (96 h, Brachydanio rerio), (Fisch): 0,033 mg/l 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether: EC50 (48 h, Daphnia magna): 0,51 mg/l IC50 (72 h, Scenedesmus subspicatus): 2,09 mg/l LC50 (96 h, Cyprinodon variegatus), (Fisch): 3,94 mg/l 12.2. Persistence and degradability:
No data available. 12.3. Bioaccumulative potential:
No data available. 12.4. Mobility in soil:
No data available. 12.5. Results of PBT and vPvB assessment:
No data available. 12.6. Other adverse effects:
Do not flush into surface water or sanitary sewer system. UNICHEM d.o.o.
SAFETY DATA SHEET
Date of compilation: Sinja Gorica 2, 1360 Vrhnika Tel: 01/7558-150Fax: 01/7558-155 EFFECT MICROTECH CS
Revision: 19.01.2012 Version no.: 001 SECTION 13: Disposal considerations
13.1. Waste treatment methods:

Reuse, when possible. Product residues should be considered special hazardous waste. The hazard level of waste containing this product should be evaluated according to applicable regulations. Disposal must be performed through an authorized waste management firm, in compliance with national and local regulations. CONTAMINATED PACKAGING Contaminated packaging must be recovered or disposed of in compliance with national waste management regulations. SECTION 14: Transport information

14.1. UN number:
14.2. UN proper shipping name:
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID 14.3. Transport hazard class(es):
14.4. Packing group:
14.5. Environmental hazards:
Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 14.6. Special precautions for user:
No data available. 14.7. Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code:
No data available. It is valid for ADR/RID, IMDG/ADN. SECTION 15: Regulatory information

15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture:
No data available.
15.2. Chemical safety assessment:

A Chemical Safety Assessment has not been carried out. UNICHEM d.o.o.
SAFETY DATA SHEET
Date of compilation: Sinja Gorica 2, 1360 Vrhnika Tel: 01/7558-150Fax: 01/7558-155 EFFECT MICROTECH CS
Revision: 19.01.2012 Version no.: 001
SECTION 16: Other information
Legend to abbreviations and acronyms used in the safety data sheet:
ADR - European Agreement concerning the International Carriage of Dangerous Goods by Road
RID - Regulations Concerning the International Transport of Dangerous Goods by Rail
CAS - Chemical Abstracts Service
IMDG - International Maritime Code for Dangerous Goods
LC50 - Lethal concentration, 50 percent
LD50 - Lethal dose, 50 percent
Literature references and sources for data:
- Commission Regulation (EU) No 453/2010 of 20 May 2010 amending Regulation (EC) No 1907/2006
of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and
Restriction of Chemicals (REACH)
- Regulation (EC) no 1907/2006 of the European parliament and of the council of 18 December 2006
concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH),
establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council
Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive
76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC
- Regulation (EC) No 1272/2008 of the European parliament and of the council of 16 December 2008
on classification, labeling and packaging of substances and mixtures, amending and repealing
Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006).
List of relevant R-phrases and hazard statements:
N - Dangerous for the environment
Xn - Harmful
R20/22 Harmful by inhalation and if swallowed.
R43 May cause sensitization by skin contact.
R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
environment.
H332 Harmful if inhaled.
H302 Harmful if swallowed.
H317 May cause an allergic skin reaction.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.
Advice on any training appropriate for workers to ensure protection of human health and the
environment:
Workers should be trained avoid skin contact.
All the information of this safety data sheet is based on our actual knowledge as well as on EEC
regulations.
The product has not to be employed for different uses than those indicated in section 1.


Source: http://www.eandspestsolutions.co.uk/wp-content/uploads/2015/07/MSDS-Effect-Microtech-CS-19.1.12.pdf

0610_y15_sy.indd

For examination in June and November 2015 This syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate (QN: ###/###/#). Cambridge Secondary 2 Changes to syllabus for 2015 This syllabus has been updated, but there are no significant changes. Cambridge International Examinations retains the copyright on all its publications. Registered Centres are permitted to copy material from this booklet for their own internal use. However, we cannot give permission to Centres to photocopy any material that is acknowledged to a third party even for internal use within a Centre.

jhskincareclinic.co.uk

NOVEL RETINOID ESTER IN COMBINATION WITH SALICYLIC ACID FOR THE TREATMENT OF ACNE PRIMARY AUTHOR: Zoe Draelos MD CO-AUTHORS: Joseph Lewis BS; Laura McHugh MS; Arthur Pellegrino BS; Lavinia Popescu MS, MBA combining the RC induced normalization of cellular differentiation, AHA induced exfoliation in hydrophilic Retinoids (RC), alpha hydroxy acids (AHA), and salicylic acid (SA) have therapeutic benefit in acne treatment